Ginsenosides

Ginsenosides

Product Name: Ginsenosides
Other Name: Ginseng extract
Appearance: Brown yellow powder
CAS NO: 78214-33-2

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Product details

Product Name: Ginsenosides

Other Name: Ginseng extract

Appearance: Brown yellow powder

CAS NO: 78214-33-2

MF: C38H42N2O6

MW: 622.73

Test Method: UV

Physical Property: ssolves in 80 ° C Water, easily soluble in ethanol.

Function: 

1. Enhancing immunity

2. Anti-oxidant

3. Relieving physical fatigue

4. Lowering blood glucose 

Packing:

1.20mg/vial,1g/vial,5g/vial,10g/vial.       

2.aluminum foil bag.

3.25kg paper drum with double plastic food grade bags inside.

4. pharmaceutical aluminum tin.

5. according to customer request.

Description:

Ginseng,is any one of the 11 species of slow-growing perennial plants with fleshy roots, belonging to the genus Panax of the family Araliaceae.

Ginseng is found in North America and in eastern Asia (mostly Korea, northeast China, Bhutan, eastern Siberia), typically in cooler climates. Panax vietnamensis, discovered in Vietnam, is the southernmost ginseng known. This article focuses on the series Panax ginsengs, which are the adaptogenic herbs, principally Panax ginseng and P. quinquefolius. Ginseng is characterized by the presence of ginsenosides and gintonin.

Siberian ginseng (Eleutherococcus senticosus) is in the same family, but not genus, as true ginseng. Like ginseng, it is considered to be an adaptogenic herb. The active compounds in Siberian ginseng are eleutherosides, not ginsenosides. Instead of a fleshy root, Siberian ginseng has a woody root.

Ginsenosides or panaxosides are a class of natural product steroid glycosides and triterpene saponins. Compounds in this family are found almost exclusively in the plant genus Panax (ginseng), which has a long history of use in traditional medicine that has led to the study of pharmacological effects of ginseng compounds. As a class,ginsenosides exhibit a large variety of subtle and difficult-to-characterize biological effects when studied in isolation.

Ginsenosides can be isolated from various parts of the plant, though typically from the roots, and can be purified by column chromatography.The chemical profiles of Panax species are distinct; although Asian ginseng, Panax ginseng, has been most widely studied due to its use in traditional Chinese medicine, there are ginsenosides unique to American ginseng (Panax quinquefolius) and Japanese ginseng (Panax japonicus). Ginsenoside content also varies significantly due to environmental effects.

Ginsenosides are named according to their retention factor value in thin layer chromatography (TLC). They can be broadly divided into two groups based on the carbon skeletons of their aglycones: the four-ring dammarane family, which contains the majority of known ginsenosides, and the oleanane family. The dammaranes can be further subdivided into two main groups, the protopanaxadiols and protopanaxatriols, with other smaller groups such as the ocotillol-type pseudoginsenoside F11 and its derivatives.

Most studies of the biological effects of ginsenosides have been in cell culture or animal models and thus their relevance to human biology is unknown. Effects on the cardiovascular system, the central nervous system, the immune system have been reported, primarily in rodents. Antiproliferative effects have also been described.

Two broad mechanisms of action have been suggested for ginsenoside activity, based on their similarity to steroid hormones. They are amphiphilic and may interact with and change the properties of cell membranes.Some ginsenosides have also been shown to be partial agonists of steroid hormone receptors. It is not known how these mechanisms yield the reported biological effects of ginsenosides. The molecules as a class have low bioavailability due to both metabolism and poor intestinal absorption.

 


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